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Actos Bladder Cancer Side Effects

The drug Actos, which is the brand name version of the chemical pioglitazone, has been prescribed for the treatment of diabetes since it was released in 1999. In recent years, it became the most widely used diabetes drug in the world after rival Avandia was linked to heart injury.

Now, researchers in the United States, Europe and Canada have warned that Actos may also present serious danger to patients, as long-term use has been associated with Actos bladder cancer. Experts fear as many as 10,000 patients may eventually be affected.

Bladder cancer is a severe form of cancer which attacks the lining of the bladder. It can affect the function of the organ and spread the disease to other organs nearby. While bladder cancer affects nearly 70,000 people each year, it is considered highly treatable if discovered early.

Common symptoms of Actos bladder cancer may include:

  • Frequent or painful urination
  • Blood in urine or discoloration of urine
  • Back pain
  • Abdominal pain
  • Urinary tract infection

If you have experienced any of these symptoms after taking Actos, it is important to speak with a doctor as soon as possible. You may also be eligible for compensation from the manufacturer, Takeda Pharmaceuticals, for their failure to warn of the risks of Actos bladder cancer.

If you or a loved one have been diagnosed with bladder cancer after taking Actos, it is important to speak with a lawyer about your legal options as soon as possible. Time to file a claim is limited. Contact us today.

Although the FDA announced in 2010 it was studying the safety of Actos due to concerns of bladder cancer, no warning was made until June of 2011. At that time, the European Medicines Agency published a French study which discovered those taking Actos for more than a year had as much as a 40% increased occurrence of bladder cancer.

Both France and Germany subsequently banned new prescriptions of Actos due to concerns of bladder cancer. While the FDA and EMA issued consumer safety alerts and required label changes to address the risks, they allowed it to remain on the market.

In April of 2012, Health Canada became the latest to warn of Actos bladder cancer, after a study by Montreal’s McGill University showed the diabetes drug may be linked to as much as a 83% increase in bladder cancer.

Researchers at McGill proposed that Actos may contribute to bladder cancer by forming crystal formations in the organ which can cause chronic irritation. However, they cautioned that further research is needed to establish any definite causation.

Those dealing with bladder cancer may require extensive and ongoing treatment such as surgery, chemotherapy, vaccine therapy, immunotherapy and radiation therapy. 

If you or a loved one has been affected by this disease after taking Actos, it is important to speak with a lawyer. They can explain the liability of Takeda for failing to warn patients of the risks of Actos, and for continuing to sell it despite knowing the dangers. A lawyer can also discuss the current litigation, whether your case qualifies, and how long you have to take action.

The Drug Risk Resource Center cautions victims that they should seek a lawyer with the resources and experience necessary for complex defective drug litigation. DrugRisk only recommends lawyers and law firms who have already handled Actos lawsuits.

Contact us today for more information on the research, side effects and litigation news related to Actos, or to speak with a lawyer. We are available 24 hours a day to provide help.